However, a head-to-head trial is required to directly compare the effectiveness of the two drugs.
This isnt the first head-to-head trial comparing the two drugs.
It would be interesting to see the report on side effects.

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While semaglutide works by activating GLP-1 receptors, tirzepatide mimics both GLP-1 and a second hormone called GIP.
Hurtado Andrade said anticipated weight loss is just one factor to consider when choosing a GLP-1 medication.
However, if someone has pre-established cardiovascular disease, semaglutide may be a better option, she said.
Shared decision-making is the most important aspect of weight management to increase the long-term chances of success.
Cost and accessibility can also factor into the decision-making process.
Talk to a trusted health provider about how to create a medical plan that best suits your health needs.
2022;39(6):2452-2467. doi:10.1007/s12325-022-02153-x